Alles wat je moet weten over Gianotti-Crosti en huidziekten

StatPearls [Internet].

Jessica Snowden , Ashley S. Rice , Hasnain A. Syed , Noreen E. O'Shea .

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Last Update: March 1, 2024 .

Papular acrodermatitis of childhood (Gianotti-Crosti syndrome) is a benign, self-limiting rash that occurs in childhood. It exhibits a distinct acral distribution, comprising monomorphic skin-colored to pink-red papules primarily found on the face, buttocks, and extremities' extensor surfaces. The condition is associated with multiple viral illnesses, including Epstein-Barr virus, cytomegalovirus, coxsackievirus, adenovirus, influenza, enteroviruses, echovirus, hepatitis A virus, herpes simplex viruses, human herpesvirus 6, HIV, mumps, parainfluenza virus, parvovirus B19, poxviruses, respiratory syncytial virus, and rotavirus. Additionally, it has been reported after vaccination, including influenza, Calmette-Guerin bacillus, diphtheria-pertussis-tetanus, poliomyelitis, hepatitis B, Japanese encephalitis, and measles vaccines. In the United States, the Epstein-Barr virus is the most commonly reported cause of papular acrodermatitis of childhood, however, in many cases, no infectious trigger is identified.

This activity reviews the evaluation and management of papular acrodermatitis of childhood, as well as its diverse viral associations and potential correlation with vaccinations. Learners will explore the syndrome's evolving etiology and engage with current evidence-based practices for diagnosing it, focusing on the distinguishing features of the rash and its associated systemic symptoms. Additionally, the session highlights the self-resolving nature of the rash and the role of the interprofessional team in treating patients with this condition.

Evaluate the presentation of a patient with papular acrodermatitis of childhood (Gianotti-Crosti syndrome), distinguishing it from other pediatric rashes like viral exanthems, allergic reactions, or drug eruptions.

What Is the Treatment for Gianotti-Crosti Syndrome?

The main symptom -- the rash -- will go away on its own. But if it’s itchy, you can use over-the-counter anti-itch treatments to ease the symptoms. Your doctor may suggest oral antihistamines if topical treatments don't help. Cool compresses may also reduce itching.

If your child has a fever, ask your doctor about using a fever reducer such as acetaminophen or ibuprofen. Ask about appropriate dosing for your child's age. Make sure your child drinks plenty of fluids, since fevers can be dehydrating.

Gianotti-Crosti syndrome is not contagious, so you don't need to isolate your child while they have the rash. In fact, the rash usually appears after the child has stopped being contagious with the virus that triggered the syndrome. Your child can participate in activities while the rash is still present, though you may need a note from your doctor to explain the situation.

Introduction

Figure 1

Anterior knee showing multiple maculopapular lesions measuring about 5-10 mm in diameter and with few scarifications marks.

Figure 2

Bilateral anterior legs showing multiple isolated and coalesced maculopapular lesions measuring about 5-10 mm in diameter.

Figure 3

Right anterior leg showing multiple isolated papular lesions measuring about 5-7 mm in diameter with sparse areas of hyperpigmentation.