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Alles Wat U Moet Weten Over Urticaria Factitia - Huidziekte en Behandeling

A csalánkiütés kezelése és kórlefolyása

A kezelésben legfontosabb a kiváltó ok kerülése. Sok esetben segít az ún. mediátormentes diéta tartása, nem szabad füstölt húsokat, halat, belsőségeket, csalánt gyakran okozó zöldségeket, gyümölcsöket (paradicsom, zeller, dió, mogyoró, eper, ananász, stb.) enni.

A gyógyszerek közül jó hatásúak a szájon át alkalmazott antihisztaminok. A modern készítményeket naponta egyszer kell bevenni, nem álmosítanak, kevésbé befolyásolják a munkavégző-képességet, mint a korábban használt szerek. Ha nyugtalanság, esetleg depresszió kíséri a tüneteket, kiegészítésként antidepresszáns gyógyszerek adhatók. Csak súlyos, indokolt esetben helyes az ún. szteroidok alkalmazása: főként egyszeri nagyobb, ún. lökéskezeléssel. Hosszabb távon ugyanis számolni kell a szteroidok mellékhatásaival is.

How is urticaria diagnosed?

Urticaria is diagnosed in people with a history of weals that last less than 24 hours with or without angioedema. A medication and family history should be elicited. A thorough physical examination should be undertaken.

Skin prick tests and radioallergosorbent tests (RAST) or CAP fluoroimmunoassay may be requested if a drug, latex, or food allergy is suspected in acute urticaria.

There are no routine diagnostic tests in chronic spontaneous urticaria apart from blood count and autologous serum skin test is sometimes carried out in chronic spontaneous urticaria, but its value is uncertain. It is positive if an injection of the patient's dermographism or applying an ice cube in suspected cold urticaria.

Investigations for a autoinflammatory disease should be undertaken in urticaria patients with fever, joint or bone pain, and Biopsy of urticaria can be non-specific. The urticarial vasculitis.

What is the outlook for chronic urticaria?

Acute urticaria resolves in hours to days but is often recurrent. Although chronic urticaria clears up in most cases, 15% continue to have wealing at least twice weekly after two years.

Bibliography

  • Cicardi M, Aberer W, Banerji A, et al. Classification, diagnosis, and approach to treatment for angioedema: consensus report from the Hereditary Angioedema International Working Group. Allergy . 2014,69(5):602–16. doi:10.1111/all.12380. PubMed
  • Grattan CE, Humphreys F, British Association of Dermatologists Therapy Guidelines and Audit Subcommittee. Guidelines for evaluation and management of urticaria in adults and children. Br J Dermatol . 2007,157(6):1116–23. doi:10.1111/j.1365-2133.2007.08283.x. PubMed
  • Greenberger PA. Chronic urticaria: new management options. World Allergy Organ J . 2014,7(1):31. doi:10.1186/1939-4551-7-31. Journal
  • Jáuregui I, Ortiz de Frutos FJ, Ferrer M, et al. Assessment of severity and quality of life in chronic urticaria. J Investig Allergol Clin Immunol. 2014,24(2):80–6. PubMed Central
  • Maurer M, Rosén K, Hsieh HJ, et al. Omalizumab for the treatment of chronic idiopathic or spontaneous urticaria [published correction appears in N Engl J Med. 2013 Jun 13,368(24):2340–1]. N Engl J Med. 2013,368(10):924–35. doi:10.1056/NEJMoa1215372. PubMed
  • Radonjic-Hoesli S, Hofmeier KS, Micaletto S, Schmid-Grendelmeier P, Bircher A, Simon D. Urticaria and angioedema: an update on classification and pathogenesis. Clin Rev Allergy Immunol . 2018,54(1):88–101. doi:10.1007/s12016-017-8628-1. PubMed
  • Techasatian L, Phungoen P, Chaiyarit J, Uppala R. Etiological and predictive factors of pediatric urticaria in an emergency context. BMC Pediatr. 2021,21(1):92. doi:10.1186/s12887-021-02553-y. Journal

On DermNet

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Who gets urticaria and why?

One in five children or adults has an episode of acute urticaria during their lifetime. It affects all races and both sexes.

Angioedema is more often eyelids and palate , or Serum sickness due to blood transfusion and serum sickness-like reactions due to certain drugs cause acute urticaria leaving bruises, fever, swollen glands , joint pain and swelling.

The weals are more persistent in chronic spontaneous urticaria, but each individual analogue

The emotional impact of urticaria and its effect on quality of life should also be assessed. The Dermatology Life Quality Index (DLQI) and CU-Q2oL, a specific questionnaire for chronic urticaria, have been validated for chronic urticaria, where sleep disruption is a particular problem.

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